I develop and analyze biophysically-constrained large-scale computational models of the nervous system. In previous work, I studied the olfactory bulb, addressing the roles of mitral, tufted, and granule cells along with glomerular layer circuitry.
Currently, I investigate the piriform cortex, addressing the functional differences between semilunar, superficial pyramidal, and deep pyramidal cells, and the interneurons that shape their response properties. More broadly, I am working on a model to better understand the organization of the piriform cortex and how it contributes to selective odor discrimination, learning, and signal restoration. I am particularly interested in the coordinated cellular and synaptic mechanisms that underlie gamma and beta oscillations and interareal synchronization.