Jesse Werth, PhD student in the lab, received NRSA fellowship support (2019-2022) from the NIDCD for his project Dynamics of spike timing in olfactory bulb coding and neuromodulation.
The project uses in vitro slices of living olfactory bulb tissue to ask how temporally regulated patterns of spike timing communicate sensory information. Realistic odor-like input patterns are delivered to the optogenetically sensitive slice using spatiotemporal patterns of light stimulation customized for each slice. Recordings are made using a 120-channel planar multielectrode array that records principal neuron action potentials and local field potentials.