In my research, I focus on the neural basis of sensory information processing, using olfaction as a model system. I am primarily interested in the relationship between perceptual qualities, as measured by behavioral experiments, and neural activity patterns, as observed electrophysiologically. My present work concerns how the central nervous system neuromodulators acetylcholine and noradrenaline, both of which have been implicated in memory deficits such as those symptomatic of Alzheimer’s disease, influence the representation and storage of olfactory information. This approach necessitates coordinated behavioral and electrophysiological experiments based on predictive theories.
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